After using Picard for the first time after booting my Mac, Picard fails to open a second or subsequent time.

I tried deleting and reinstalling, which works, one time only.

I found that Picard creates the file ~/.config/MusicBrainz/.Picard.ini.synclock when successfully started. After closing Picard this file is not removed. When I manually remove the file, Picard starts successfully.