Copied nightly build to my desktop and tried to run it. Here are the message I see on the console.

May 18 16:10:48 officeimac.local MusicBrainz Picard[19777] <Notice>: Traceback (most recent call last):
May 18 16:10:48 officeimac.local MusicBrainz Picard[19777] <Notice>: File "/Users/jeffreyh/Desktop/MusicBrainz Picard.app/Contents/Resources/_boot_.py", line 341, in <module>
May 18 16:10:48 officeimac.local MusicBrainz Picard[19777] <Notice>: _run()
May 18 16:10:48 officeimac.local MusicBrainz Picard[19777] <Notice>: File "/Users/jeffreyh/Desktop/MusicBrainz Picard.app/Contents/Resources/_boot_.py", line 336, in _run
May 18 16:10:48 officeimac.local MusicBrainz Picard[19777] <Notice>: exec(compile(source, path, 'exec'), globals(), globals())
May 18 16:10:48 officeimac.local MusicBrainz Picard[19777] <Notice>: File "/Users/jeffreyh/Desktop/MusicBrainz Picard.app/Contents/Resources/tagger.py", line 7, in <module>
May 18 16:10:48 officeimac.local MusicBrainz Picard[19777] <Notice>: from picard.tagger import main
May 18 16:10:48 officeimac.local MusicBrainz Picard[19777] <Notice>: File "picard/tagger.pyo", line 54, in <module>
May 18 16:10:48 officeimac.local MusicBrainz Picard[19777] <Notice>: File "picard/log.pyo", line 24, in <module>
May 18 16:10:48 officeimac.local MusicBrainz Picard[19777] <Notice>: File "picard/util/_init_.pyo", line 22, in <module>
May 18 16:10:48 officeimac.local MusicBrainz Picard[19777] <Notice>: ImportError: No module named ntpath
May 18 16:10:49 officeimac.local MusicBrainz Picard[19777] <Notice>: 2014-05-18 16:10:49.009 MusicBrainz Picard[19777:507] MusicBrainz Picard Error